RT-3 20mg (GLP-3)
Synthetic peptide with triple agonist receptor activity Standard 20mg research quantity for multi-receptor pathway studies 99% pure (HPLC verified) · Third-party lab tested · Lyophilized powder For in vitro receptor interaction studies only
For laboratory research use only. Not for human or veterinary consumption. SKU RT20.
Product details.
What the third receptor adds
The glucagon receptor is the differentiator. Sema (GLP-1 only) and TZ-2 (GLP-1 + GIP) leave it untouched. But glucagon receptor activation drives energy expenditure through hepatic and thermogenic pathways that neither GLP-1 nor GIP can access. Preclinical data shows that adding this third receptor target to the dual GIP/GLP-1 framework produces the most pronounced effects on metabolic parameters of any approach studied to date.
All three receptors are G-protein coupled and signal through cAMP/PKA cascades, but their tissue distribution and downstream effects are distinct. GLP-1 receptors dominate in the pancreas and hypothalamus. GIP receptors are concentrated in adipose tissue and the CNS. Glucagon receptors are heavily expressed in the liver. RT-3 reaches all three tissue compartments.
Specifications
| Classification | Triple GLP-1/GIP/Glucagon receptor agonist |
| Form | Lyophilized powder |
| Quantity | 20mg per vial |
The incretin ladder: Sema vs TZ-2 vs RT-3
Heritage Labs USA stocks all three tiers. Sema is the selective GLP-1 agonist (31 amino acids, one receptor). TZ-2 is the dual GIP/GLP-1 agonist (39 amino acids, two receptors). RT-3 is the triple agonist (three receptors). Comparative preclinical literature documents a clear stepwise increase in metabolic parameter engagement as you move from single to dual to triple activation.
Frequently paired with
- Cagri 5mg — Hindbrain satiety pathway via amylin receptors
- MOTS-C 10mg — AMPK-mediated metabolic signaling
- NAD+ 500mg — Cellular energy metabolism and sirtuin pathways
Quality and testing
Third-party tested by an independent lab for identity, density and purity. Certificates of analysis are published on the product page and in the COA portal. Manufactured to research-grade standards and shipped in protective packaging.
Storage
- Lyophilized: -20°C for long-term stability
- Reconstituted: 2-8°C, use within 30 days
For laboratory research use only. Not for human or veterinary use.
FDA Disclaimer. All products are for research use only (RUO) as defined by the FDA — not for diagnostic, human, or veterinary use. These products have not been evaluated and have not been approved by the U.S. Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.
Heritage Labs is a chemical supplier providing products strictly for laboratory research, analytical, and in-vitro purposes; it is not a compounding pharmacy or compounding facility under Section 503A, nor an outsourcing facility under Section 503B, of the Federal Food, Drug, and Cosmetic Act.