Retatrutide 5mg

Synthetic peptide with triple agonist receptor activity Engineered for multi-receptor pathway research Research-grade · Lyophilized powder For in vitro receptor interaction studies only

$61.99 In stock

Research-Grade CompoundsManufactured to research-grade standards for laboratory research use only.

Discreet ShippingEvery order ships in plain, protective packaging.

In-House FulfillmentOrders are inspected, packed, and shipped directly by the Heritage Labs team.

Same-day dispatch on orders before 12:00 PM ET, Mon–Fri. Discreet, plain packaging.

In-House Fulfillment Orders are inspected, packed, and shipped directly by the Heritage Labs team.

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For laboratory research use only. Not for human or veterinary consumption. SKU RT5.

Overview

Product details.

RT3 5mg — Triple Receptor Agonist

Single receptor. Dual receptor. Triple receptor. That is the trajectory of incretin-based research over the past decade, and RT3 represents the current frontier. By simultaneously engaging GLP-1, GIP, and glucagon receptors, this compound activates the most comprehensive metabolic signaling network available in a single molecule.

Research-Grade Compounds

Manufactured to research-grade standards for laboratory research use only.

Discreet Shipping

Every order ships in plain, protective packaging.

In-House Fulfillment

Orders are inspected, packed, and shipped directly by the Heritage Labs team.

What the third receptor adds

The glucagon receptor is the differentiator. SM1 (GLP-1 only) and TR2 (GLP-1 + GIP) leave it untouched. But glucagon receptor activation drives energy expenditure through hepatic and thermogenic pathways that neither GLP-1 nor GIP can access. Preclinical data shows that adding this third receptor target to the dual GIP/GLP-1 framework produces the most pronounced effects on metabolic parameters of any approach studied to date. All three receptors are G-protein coupled and signal through cAMP/PKA cascades, but their tissue distribution and downstream effects are distinct. GLP-1 receptors dominate in the pancreas and hypothalamus. GIP receptors are concentrated in adipose tissue and the CNS. Glucagon receptors are heavily expressed in the liver. RT3 reaches all three tissue compartments.

Specifications

Classification	Triple GLP-1/GIP/Glucagon receptor agonist
Form	Lyophilized powder
Quantity	5mg per vial

The incretin ladder: SM1 vs TR2 vs RT3

Heritage Labs USA stocks all three tiers. SM1 is the selective GLP-1 agonist (31 amino acids, one receptor). TR2 is the dual GIP/GLP-1 agonist (39 amino acids, two receptors). RT3 is the triple agonist (three receptors). Comparative preclinical literature documents a clear stepwise increase in metabolic parameter engagement as you move from single to dual to triple activation.

Frequently paired with

Cagrilintide 5mg — Hindbrain satiety pathway via amylin receptors
MOTS-C 10mg — AMPK-mediated metabolic signaling
NAD+ 1000mg — Cellular energy metabolism and sirtuin pathways

Quality and testing

Every Heritage Labs compound is manufactured to research-grade standards and shipped in protective packaging.

Storage

Lyophilized: -20°C for long-term stability
Reconstituted: 2-8°C, use within 30 days

For laboratory research use only. Not for human or veterinary use.

For laboratory research use only. Not for human or veterinary use. This product is not a drug or supplement and is not intended to diagnose, treat, cure, or prevent any disease.

FDA DISCLAIMER: All products are intended for research use only as defined by the FDA. Not for use in diagnostic procedures, human use, or veterinary use. Products have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. All products sold by Heritage Labs are intended strictly for laboratory research, analytical, or in-vitro purposes only. Heritage Labs operates as a chemical supplier and is not a compounding pharmacy or chemical compounding facility as defined under Section 503A of the Federal Food, Drug, and Cosmetic Act. Additionally, Heritage Labs is not classified as an outsourcing facility under Section 503B of the same Act. The statements on this website have not been evaluated by the U.S. Food and Drug Administration. Our products are not intended to diagnose, treat, cure, or prevent any disease.